Esonitro君柔科技

Core Technology

NeuroWorm Bioinspired Worm-Like Dynamic Electrode

Breaking the "static" tradition of implantable electrodes and opening a new direction for the research and application of brain-computer interface electrodes.

Technology Paradigm

Technology Name

NeuroWorm Bioinspired Worm-Like Dynamic Electrode

Core Innovation

This research is the first to propose the "dynamic electrode" paradigm for brain-computer interfaces, breaking the "static" tradition of implantable electrodes and opening a new direction for the research and application of brain-computer interface electrodes.

Publication

The research was published in Nature, 2025, under the title:

A movable long-term implantable soft microfibre for dynamic bioelectronics

Nature, 2025
NeuroWorm fabrication diagram: rolling SEBS and Au films, with biopotential sensor and capacitive strain sensor structures

Technical Advantages

Four Core Advantages

Systematic innovation from implantation to long-term stability.

Minimally Invasive Implantation

As fine as a human hair with electrode sites of only 5 μm, soft and stretchable — low implantation-related tissue trauma and low risk.

Dynamically Adjustable

Freely drivable, solving the problems of electrode displacement and difficult repositioning in conventional electrodes.

Long-Term Stability

Theoretical lifespan of 10+ years with 1.5 years of verified long-term stability, addressing signal degradation in chronic implants.

Biocompatibility

Gold electrodes offer top biocompatibility, and SEBS insulation keeps tissue damage and immune-response risks low.

Technology Comparison

vs. Traditional Approaches

Differentiating advantages compared with conventional BCI electrode approaches.

Limitations of Traditional Approaches

  • Non-invasive

    Signals attenuate through the skull, limiting resolution and localization

  • Flexible Electrodes

    Fixed position, cannot be dynamically adjusted or optimized long-term

  • Silicon-based Electrodes

    Rigid and unbendable, notable long-term immune response

  • Semi-invasive

    Still requires craniotomy, higher trauma and risk than vascular access

Esonitro Core Advantages

  • Minimally invasive

    Hair-thin implant via vascular access, no craniotomy

  • Stable signals

    No signal decay over long-term implantation, 10+ year lifetime

  • Flexible

    Freely steerable, position adjustable at any time

  • Multi-electrode collaboration

    Electrode arrays covering multiple deep-brain targets

  • Whole-brain signal recording and writing

    Both recording and neuromodulation across the whole brain

Derivative Technologies

Extending from the Core Paradigm

Technologies developed from the dynamic electrode paradigm.

Photograph of a flexible stretchable electrode with a wave-shaped structure

Flexible Stretchable Electrodes

Soft and stretchable electrodes for EMG and other applications, already commercially deployed.

Photograph of a hair-penetrating electrode with an array of fine filaments

Hair-Penetrating Electrodes

Viscoelastic hair-penetrating electrodes, developed in cooperation with leading international companies.